Elmiron, which was approved in 1996 by the Food and Drug Administration, is commonly used to treat a condition named painful bladder. For the treatment of interstitial cystitis, more generally referred to as painful bladder syndrome, Elmiron is prescribed.
Recent studies have shown, however, that chronic drug use can put patients at increased risk for eye disease, especially a rare type of macular degeneration. Findings from the American Academy of Ophthalmology have identified a correlation between long-term Elmiron use and maculopathy formation, which can lead to significant vision loss and even blindness.
Elmiron is indeed a frightening and destructive drug. If you or a loved one are having trouble reading, blurred vision, maculopathy, or irreversible loss of vision due to exposure to pentosan polysulfate sodium (PPS), it must have been tough. In this article, Elmiron’s symptoms, effects, studies are discussed, and what you should know about Elmiron lawsuits.
What Is Painful Bladder Syndrome (PBS)?
Painful Bladder Syndrome (PBS) or Interstitial Cystitis (IC) can cause an individual’s bladder to feel discomfort. It can cause mild to severe pain and pressure which makes it difficult, especially when the individual may frequently go and hurry to the restroom every once in a while.
PBS is not caused by an infection, although, as an infection of the urinary tract or UTI, it may sound like a bladder infection.
The cause for PBS to occur is unknown, but having PBS means that the inner lining of the bladder is not working and functioning properly. These signs are mixed up with interstitial cystitis, and you experience the need to urinate more frequently and with lower urine volumes than other individuals.
Interstitial cystitis affects women more often and can have a lasting effect on the quality of life. Sadly, there is no cure, but therapies can relieve symptoms. The nerves in the bladder wall are hypersensitive so that the usual sensation of filling the bladder can be tragic.
Even more, it can cause inflammation or, worse, an allergic reaction response. Both of these conditions can be present and maybe a risk to the bladder. Some individuals report having PBS, because of an incident that they face like other bladder infections.
They even consider that it is because of severe trauma, following an injury to the bladder, although this is not always happening for all people who have PBS. In individuals who have bowel problems, experiencing fatigue, and other pain disorders, PBS is more common. Why these issues are happening together is not clear.
When the bladder fills, individuals with PBS may have bladder pain. In some instances, some individuals experience discomfort in their genitalia. It can also affect their back, as well as when they are in a sitting position. The discomfort can be persistent or come and go and can alter in intensity.
In a case where an individual has PBS, they are more frequent to go to the restroom to pee. Even more, they are urinating more than they drink, which is bad. Around seven times a day, an individual may pee and go to the restroom once or twice every night.
An individual that suffers from PBS needs to go to the restroom more frequently. It is an urgent need for them to hurry to go to the restroom just to pee. Some people even experience peeing once more after they have done it, and they do it because they have a relentless urge that never goes away.
Many individuals with PBS realize that their symptoms are made worse by such foods or beverages. When individuals with PBS are facing difficult times that cause them to suffer emotionally or physically, symptoms can be worse.
Even for women in their red days, the symptoms can change. After sex, some women with PBS have discomfort. There are even cases where women with PBS can experience pain during sex.
To discuss symptoms, first, the doctor will administer an examination on you. Next, you will take urine tests. Because of this, an office visit is highly necessary. Such tests will clear the case- that there is no other condition that is causing pain, discomfort, and frequent urination of the bladder.
What is Elmiron?
Elmiron is taken orally, and its other name is pentosan polysulfate sodium. Elmiron has been around for 25 years, as it was approved by the U.S. Food and Drug Administration in 1996. For bladder pain relief or inflammation associated with interstitial cystitis, Elmiron is prescribed.
This medication works by forming a coating on the bladder wall and protecting it from irritation and damage. In addition, it is a feeble “blood thinner” and can increase the risk of bruising/bleeding.
Elmiron is a weak anticoagulant. This effect increases bleeding times. At a daily dose of 300 mg, findings suggest that rectal hemorrhage was recorded in 6.3 percent of patients as an adverse event. There were also findings regarding gum bleeding. It is identified as a bleeding complication caused by taking Elmiron.
Hemorrhage should be evaluated in patients undergoing invasive procedures or underlying coagulopathy symptoms or another elevated risk of bleeding. Before taking Elmiron, patients with illnesses such as aneurysms, thrombocytopenia, hemophilia, gastrointestinal ulceration, polyps, or diverticula should be carefully examined.
Medical examinations (such as eye exams) may be conducted with extended care when you are taking this drug. Keep all medical and laboratory appointments in place. For more information, contact your doctor.
After Effects Of Elmiron
Hair loss, diarrhea, nausea, blood in the stools, fever, rash, upset stomach, irregular liver function tests, dizziness, and bruising are the most common side effects of Elmiron. It is advised to contact the doctor if these side effects persist or are bothersome, or if the stool contains blood.
Contact the nearest poison control center or emergency room immediately if you believe that anyone might have taken more than the recommended dosage of this drug. This drug is prescribed for interstitial cystitis or painful bladder syndrome (PBS). Do not take it or send the medication to anyone for another disease.
Remember that Elmiron only helps relieve symptoms. It does not treat the underlying cause. It relieves symptoms linked with interstitial cystitis, pain, and nausea caused by this medical condition. In this case, physicians choose to prescribe Elmiron (PPS).
Men and women have been prescribed Elmiron by physicians for decades to relieve the symptoms of interstitial cystitis. The latest findings and studies indicate connections between the use of Elmiron and the conditions of pigmentary maculopathy and loss of vision.
Janssen Pharmaceuticals listed a warning about the drug’s potential for causing vision loss in June 2020, following comprehensive studies and pressure from outside outlets. This places a possible risk of having one or more vision-related disorders in thousands or even hundreds of thousands of patients.
Hidden Side Effects of Elmiron
Studies have shown that Elmiron has adverse effects on vision, especially when ingested over long periods of time. Patients who were prescribed Elmiron and took it for their painful bladder syndrome or interstitial cystitis may cause them to lose their vision slowly, problems with eye adjustment to the dark, retinal damage, and many more.
Worse, it may cause them to lose their eyesight forever- or blindness, according to a 2019 study by the American Academy of Ophthalmology. If you know any Elmiron patients, it is better to tell them to report any of the side effects of Elmiron that they encounter while taking it to the U.S. Food and Drug Administration.
At the 2019 meeting of the American Academy of Ophthalmology, studies presented provide clear supporting evidence of the correlation of the bladder drug to vision loss and many other vision-threatening conditions.
Evidence Linking Elmiron To A Vision-Threatening Eye Condition
In a study conducted by Kaiser Permanente, they discovered nearly one-fourth of the patients taking Elmiron suffered from varying damage to their eyes, including but not limited to vision loss. After taking it for many months or years, it damaged the retina- which affects the eye’s ability to see and sense light.
Elmiron- a medicine commonly used for decades for bladder disease, now appears to be harmful to the retina, the tissue that senses light at the back of the eye that enables people to see. Three ophthalmologists performed a study on the patients from Kaiser Permanente in Northern California following an initial report last year that Elmiron (PPS) could be associated with retinal damage.
They noticed that there were clear signs of eye harm in about one-quarter of patients with substantial exposure to Elmiron and that this drug toxicity could trigger other recognized retinal disorders.
It’s important to take action quickly, whatever your specific circumstances are. After discovering your injuries, your state probably has a limitation period on how much time you have to sue, making it important to find the right law firm to file your Elmiron vision case as soon as possible. You can enter an Elmiron lawsuit if you have experienced retinal damage, vision loss, or other vision problems from taking Elmiron for interstitial cystitis.
Several Elmiron lawsuits have been brought against manufacturers of the prescription medication Elmiron, an approved drug by the FDA which was used to treat interstitial cystitis. These lawsuits argue that Elmiron’s makers, Janssen Pharmaceuticals and Bayer, intentionally retained details on the risks of using Elmiron, particularly an increased risk of retinal damage identified as pigmentary maculopathy.
With the support of experienced attorneys, joining an Elmiron lawsuit could be the only way to achieve reasonable and complete compensation for your vision loss associated with Elmiron. A seasoned lawyer can help you file your claim, collect facts, build your case, and seek compensatory damages for your injuries, though Elmiron litigation payout sums are not guaranteed.
Vision-threatening Maculopathy To Elmiron Exposure
Maculopathy is a progressive disease, usually, in both eyes, that can lead to vision loss. The disorder affects a section of the eye called the macula at the back of the retina. The macula regulates the ability to read, to see fine object information, identify faces and colors, and focus on central vision.
Research indicates that 35 cases from a cohort of 404 patients with PPS exposure were retrospectively reported as having characteristic findings associated with this rare maculopathy. The clinical presentation of the patients was trouble reading and prolonged adaptation to darkness.
The maculopathy is manifested as blurred vision and prolonged dark adaptation. Even more, it is identified by an extensive ophthalmic examination and imaging. There were changes in the RPE and photoreceptor-RPE interface. The retinal pigment epithelium (RPE) is a highly pigmented cell monolayer that forms the outer blood-retina barrier and performs many essential functions that support the health and integrity of photoreceptors.
Know More About Elmiron Lawsuits
Since 1996, Janssen Pharmaceuticals, owned by Johnson & Johnson, has been manufacturing Elmiron. Prescription drug manufacturers such as Johnson & Johnson (owner of Janssen Pharmaceuticals) neglected to alert the public before June 2020 about many vision impairment-related Elmiron effects. In 2021, the Elmiron lawsuit is expected to expand.
Using Elmiron to treat interstitial cystitis can lead to expensive vision issues that, for years down the road, can impact your health, life, and happiness. Suppose you have taken Elmiron for interstitial cystitis-related complications and have sustained vision harm. In that case, you may be entitled to financial compensation for the costs of past and future medical care, pain and suffering (physical and mental) as a result of your illness and related medical procedures, any loss of salary, and expected earnings as a result of injury, and any other damage or loss suffered.
Bladder pain syndrome (BPS) remains a complex condition that is difficult to resolve. Moreover, there aren’t a lot of options from medications to choose from. In fact, PPS marketed as Elmiron is the only FDA-approved oral drug for IC/BPS treatment.
It is a synthetic polysaccharide that binds to urothelium, providing a protective layer that can help prevent painful inflammation from urine components. A significant connection between Elmiron and the development of conditions such as vision loss and maculopathy, a severe and often permanent eye disease, has since been verified by other findings.
There is indeed evidence that connects the long-term use of Elmiron for interstitial cystitis with various forms of damage to the eyes, including distortion of vision, progressive loss of vision, ocular toxicity, and pigmentary maculopathy.
There has been no recall of Elmiron, which is very frightening. Many studies and research were conducted that links using Elmiron to eye damage, but the Food and Drug Administration is not making a move on recalling it just yet. People were only warned about its side effects. Anyone who has been a victim will surely feel injustice about it.
To lessen the number of people who might be a victim of this terrifying drug, it is only natural to let this drug be recalled once and for all, with numerous studies and research linking chronic PPS exposure to unique pigmentary maculopathy, as well as other types of eye damage. Currently, the FDA has no plans for the manufacturer to request an Elmiron recall.
Today, Elmiron lawyers from the United States are genuinely accepting cases for clients who have used Elmiron for at least two years or more, undergone vision loss, suffered eye disorders, or vision problems related to the intake of Elmiron. In the same manner, remember that if you suffered a vision loss injury in the midst while taking it within the year after therapy finished, you might qualify for an Elmiron lawsuit.